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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Spine (Phila Pa 1976). 2013 Oct 1;38(21):1862–1868. doi: 10.1097/BRS.0b013e3182a3d3b4

Table 2.

Risk of Cancer Associated with BMP Administration in Unadjusted and Adjusted Models

Crude Hazard Ratio Adjusted Hazard Ratio

HR 95%CI HR 95%CI
Diagnosis in Follow Up
Any Cancer 0.98 0.95 1.02 0.99 0.96 1.03
Bone 0.76 0.59 1.00 0.77 0.59 1.01
Brain 0.83 0.66 1.03 0.82 0.66 1.03
Breast 1.05 0.96 1.15 1.05 0.95 1.15
Cervix Uteri 0.91 0.61 1.34 0.91 0.61 1.34
Colon and Rectum 0.99 0.88 1.11 1.00 0.89 1.12
Corpus Uteri 0.84 0.64 1.10 0.85 0.64 1.11
Esophagus 0.98 0.71 1.37 1.00 0.72 1.39
Hodgkins Lymphoma 1.09 0.96 1.25 1.10 0.97 1.26
Non Hodgkins Lymphoma 1.01 0.93 1.10 1.02 0.94 1.11
Kaposi Sarcoma 0.67 0.24 1.87 0.67 0.24 1.87
Kidney and Renal Pelvis 1.01 0.85 1.20 1.02 0.86 1.21
Larynx 0.89 0.58 1.35 0.90 0.59 1.37
Leukemia 1.06 0.88 1.28 1.08 0.90 1.30
Liver and Intrahepatic Bile Ducts 1.15 0.94 1.41 1.17 0.95 1.43
Lung and Bronchus 0.96 0.87 1.06 0.96 0.87 1.07
Melanoma 1.06 0.94 1.20 1.09 0.96 1.22
Mesothelioma 0.95 0.58 1.54 0.96 0.59 1.56
Myeloma 0.90 0.76 1.07 0.91 0.76 1.08
Oral cavity and Pharynx 0.92 0.59 1.45 0.94 0.60 1.48
Ovary 1.10 0.89 1.37 1.10 0.89 1.37
Pancreas 1.10 0.74 1.62 1.11 0.75 1.64
Prostate 0.95 0.87 1.05 0.96 0.87 1.05
Stomach 1.06 0.80 1.41 1.08 0.81 1.43
Testis 1.18 0.60 2.32 1.17 0.60 2.30
Thyroid 1.14 0.86 1.52 1.12 0.84 1.48
Urinary bladder 0.96 0.83 1.12 0.99 0.85 1.15