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. Author manuscript; available in PMC: 2014 Apr 30.
Published in final edited form as: Cell Mol Immunol. 2013 Sep 30;11(1):71–78. doi: 10.1038/cmi.2013.43

Figure 5.

Figure 5

Vaccination with CpG adjuvant reduces HBV DNA in the liver. (a) AAV/HBV (2×1010 vg)-infected mice were treated with the indicated vaccine combinations. HBV DNA levels in the liver were determined by real-time PCR at 11 weeks post-vaccination. (b) HBsAg levels in the liver were measured by ELISA at 11 weeks post-vaccination with homogenized liver tissues. (c) Immunohistochemical staining of HBcAg in the liver sections of different groups (n=3). AAV, adeno-associated virus; HBcAg, HBV core antigen; HBsAg, HBV surface antigen; HBV, hepatitis B virus.