. Author manuscript; available in PMC: 2014 Nov 1.

Published in final edited form as: Clin Nephrol. 2013 Nov;80(5):313–321. doi: 10.5414/CN107991

Table 3.

Relationship between Plasma FGF-23 Concentrations and Change in Left Ventricular Ejection Fraction during Follow-up in Chronic Dialysis Patients

Model	FGF-23 Tertiles (RU/mL) Difference (95% CI)			Log₁₀ FGF-23 Difference (95% CI)
Model	≤ 1966	1967–11492	> 11492	Log₁₀ FGF-23 Difference (95% CI)

Unadjusted	0.0 (REF)	−1.0 (−7.2 to 5.2)	−6.7 (−13.1 to −0.33)	−4.3 (−9.3 to 0.66)

Model 1	0.0 (REF)	0.13 (−6.6 to 6.9)	−8.0 (−15.5 to −0.53)	−6.5 (−11.3 to −1.73)

Model 2	0.0 (REF)	0.12 (−6.8 to 7.0)	−8.4 (−16.2 to −0.62)	−7.2 (−12.3 to −2.1)

Model 1: adjusted for age, gender, race, diabetes, hypertension, history of cardiovascular disease, body mass index, systolic blood pressure, serum albumin, hemoglobin, phosphorus, plasma 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D.

Model 2: adjusted for covariates in Model 1 plus use of angiotensin converting enzyme inhibitors, angiotensin receptor blockers and beta-blockers.