Table 2. Objective Mechanical & Imaging Findings.
| Study | No Cases | Mean BMI (kg/m2) | Type of Stenosis | CSF Opening Pressure | Mean Pressure Gradient | Number of Retreatments | Sinus Pressure | |||
|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||
| Before (cm H2O) | After (cm H2O) | Before (mm Hg) | After (mm Hg) | Before Stenting (mm Hg) | After Stenting (mm Hg) | |||||
| Ahmed et al 2011 | 52 | >30 in 47 | Ex: 11, IN: 17, Cb: 24 | 32.9 (25-55) NR in 4 | 4 /6 retreatments 23.8 (17-31) | 19.1 (4-41) | 0.6 (0-14) | 6 re-stented– 5 restenosis adjacent to stent, 1 stenosis in contralateral side | 46 w pap, 34 (15-94), 6 wo pap, 25 (18-34) | 46 w pap, 16 (11-33), 6 wo pap, 12 (7-14) |
| Albuquerque et al 2010 | 18 | NR | NR | NR | NR | NR | NR | 0 | NR | NR |
| Arac et al 2009 | 1 | 29 | CB^ | 31 | NR | 14 | 2 | 0 | 27 | 14 |
| Bussiere et al 2010 | 10 | 35.9 (27-47) | NR | Only range given (25-50) | NR | 28.25 (11-50) | 11.25 (2-23) | NR | NR | NR |
| Donnet et al 2008 | 10 | 27.3 (22-37) | NR | 40.2 (29-59) | 19 (9-19) | 19.1 (12-34) | NR | 0 | 29.2 (20-44) | NR |
| Fields et al 2011 | 15 | 39 (30-73) | NR | NR | NR | 24 (13-40) | 4 (0-9) | 2 needed VPS | NR | NR |
| He et al 2012^ | 24 | NR | NR | NR | NR | 11.7 | 7 | NR | 23 | 14.5 |
| Higgins et al 2003 | 12 | 36.9 (29-45) | NR | 33.7 (25-46) | NR | 18.9 (8-37) | 5.75 (2-15) | 2 re –stented, both in contralateral sinus | 27.2 (14-45) | 15.6 (12-23) |
| Higgins et al 2002 | 1 | 30.1 | CB^ | 35 | 13.7 | 18 | 3 | 0 | 27 | NR |
| Khalia et al 2010* | 22 | 38.2 (23-61) | NR | NR | NR | 18 pts with data 13.3 (3-40) | 18 pts with data 1.7 (0-7) | 8 re-stented, 5 stenosis adjacent to stent, 2 contralateral stenosis, 1 IJ stenosis | 18 pts with data 24 (9-51) | 18 pts with data 12 (6-24) |
| Kumpe et al 2012 | 18 | 31.6 (22.6-38) | NR | 39.6 (25-73) NR in 4 | NR | 21.4 (4-39) | 2.6 (0-7) | 2 re-treated, 1 re-stented, 1 thrombectomy downstream from stent | NR | NR |
| Lazzaro et al 2012 | 3 | 39.7 (31.5-47.7) | 1 CB, 1 Ex, 1 IN^ | 2 reported, >44 & 60 | NR | 32 (30-36) | 3.7 (1-5) | 0 | 44.7 (39-50) | 24.3 (19-33) |
| Ogunbo et al 2003 | 1 | NR | CB^ | 40 | 26 | 25 | NR | 0 | 40 | NR |
| Owler et al 2003 | 4 | 30 (23-38) | NR | 3 reported, 39 (30-48) | 3 reported, 15 (15-16) | 19 (12-25) | 0.25 (0-1) | 0 | 27.25 (18-36) | NR |
| Paquet et al 2008 | 1 | NR | NR | 30 | NR | 15 | NR | 0 | 33 | NR |
| Rajpal et al 2005 | 1 | 26.9 | CB^ | 37 | NR | 25 | NR | 0 | 35 | NR |
| Radvany et al 2013 | 12 | 32.6 (27.3-45.7) | NR | 39.4 (29-55) | NR | 12.4 (5-28) | 1.27 (0-4) | 2 re-stented – stenosis proximal to stent | NR | NR |
| Teleb et al 2012 | 1 | 28 | EX | 48 | NR | 26 | 0 | 0 | 31 | 11 |
| Zheng et al 2010 | 1 | 26.1 | IN -GR | 40 | 14.5 | 12 | 0 | 0 | 17 | NR |
|
| ||||||||||
| Before & After Treatment Significance: | Paired T-Test < 0.05 (0.002) | Paired T-Test < 0.05 (0.0001) | Paired T-Test < 0.05 (0.0001) | |||||||
^
per imaging review, the report did not report the type of stenosis
*
Case series presented as abstract at 2010 American Academy of Neurology annual meeting Poster P05.284,
Abbreviations: NO= number, NR= not reported, IN = intrinsic, GR = arachnoid granulation, EX= extrinsic (smooth gradual narrowing /tapered stenosis), CB= combined intrinsic & extrinsic