Online Appendix Table 2.
Sex-adjusted rates of hypertension, elevated levels of low lipoprotein cholesterol, type 2 diabetes, treatment and control among BMI categories, stratified by age
| % of Participants (95% CI) | |||||
|---|---|---|---|---|---|
| BMI 18.5-<25 | BMI 25-<30 | BMI ≥30 | p-value* | ||
| N=1548 | N=1327 | N=828 | |||
| <50 year | Hypertension | ||||
| Prevalence | 4.7 (3.7–5.9) | 12.3 (10.4–14.3) | 27.4 (23.9–31.2) | <0.001 | |
| Treatment | 40.5 (25.6–56.7) | 43.3 (33.3–53.8) | 45.9 (36.9–55.2) | 0.26 | |
| Control | 28.6 (16.6–43.3) | 33.9 (25.4–43.2) | 30.8 (23.8–38.6) | 0.99 | |
| Elevated LDL-C | |||||
| Prevalence | 6.0 (4.9–7.4) | 17.0 (14.8–19.3) | 24.3 (21.0–28.0) | <0.001 | |
| Treatment | 23.2 (13.9–34.9) | 36.4 (29.0–44.2) | 30.6 (23.2–39.8) | 0.48 | |
| Control | 18.4 (10.5–29.0) | 29.1 (22.5–36.3) | 25.5 (18.9–33.0) | 0.34 | |
| Diabetes | |||||
| Prevalence | † | 1.4 (0.8–2.2) | 5.6 (4.1–7.5) | <0.001 ‡ | |
| Treatment | † | 50.0 (11.8–88.2) | 39.3 (21.5–59.4) | 0.006 ‡ | |
| FPG <126 mg/dL | † | 36.4 (10.9–69.2) | 15.4 (5.9–30.5) | 0.02 ‡ | |
| 50+ year | N=910 | N=1269 | N=919 | ||
| Hypertension | |||||
| Prevalence | 26.2 (22.9–29.8) | 39.7 (36.1–43.4) | 54.1 (49.0–59.1) | <0.001 | |
| Treatment | 67.4 (56.8–76.8) | 67.5 (59.7–74.6) | 74.1 (66.0–81.2) | 0.006 | |
| Control | 37.9 (30.5–45.6) | 37.8 (32.5–43.3) | 42.5 (36.9–48.3) | 0.69 | |
| Elevated LDL-C | |||||
| Prevalence | 27.6 (24.1–31.2) | 45.7 (41.9–49.5) | 51.5 (46.5–56.4) | <0.001 | |
| Treatment | 38.5 (31.1–46.2) | 36.1 (31.2–41.3) | 44.0 (38.1–50.0) | 0.03 | |
| Control | 29.7 (23.3–36.7) | 24.5 (20.5–28.8) | 30.6 (25.7–35.7) | 0.18 | |
| Diabetes | |||||
| Prevalence | 3.2 (2.1–4.6) | 7.2 (5.8–8.8) | 18.4 (15.7–21.4) | <0.001 | |
| Treatment | 61.5 (31.6–86.1) | 48.8 (32.9–64.9) | 58.9 (46.8–70.3) | 0.43 | |
| FPG <126 mg/dL | 27.3 (10.7–50.2) | 17.3 (9.6–28.2) | 15.8 (10.3–22.7) | 0.26 | |
Abbreviations: CI, confidence interval; BMI, body mass index; LDL-C, low-density lipoprotein cholesterol; Hb A1c, Hemoglobin A1c level; FPG, fasting plasma glucose
SI conversion factor: To convert fasting plasma glucose to mmol/L, multiply mg/dL values by 0.0555
Global GEE p-value
Among participants younger than 50 years of age with a BMI 18.5-<25, there were only 5 individuals with diabetes mellitus. Of those, 5 received hypoglycemic treatment and 3 had FPG <126 mg/dL
Interpret p-value with caution as there are only small number in the cells of participants younger than 50 years of age with a BMI 18.5-<25