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. Author manuscript; available in PMC: 2006 Jan 25.
Published in final edited form as: Purinergic Signal. 2005 Sep;1(3):241–247. doi: 10.1007/s11302-005-6310-1

Figure 4.

Figure 4

Effects of MRS2179 on calcium mobilization induced by HT-AMP in astrocytoma cells. a) MRS2179 was used to antagonize the effects of the agonist HT-AMP in the calcium mobilization assay. The MRS2179 concentration was fixed at either 0, 10−6, 5 × 10−5, 10−5, or 5 × 10−4 (M) over an HT-AMP range of 10−10–10−4 (M). Increasing amounts of antagonist cause a right shift in the curves. Each experimental data point was done in duplicate and averaged. b) A Schild analysis was performed to calculate a KB of 70 nM.