. Author manuscript; available in PMC: 2015 Jan 30.

Published in final edited form as: J Proteome Res. 2014 Jan 30;13(3):1614–1623. doi: 10.1021/pr401117m

Table 1. Nitrated Peptides from the Anti-3-Nitrotyrosine Antibody–Agarose-Immunoprecipitated Brain Proteins^a.

			HIV-E		HIV-E		HIV		HIV		Control		Control		Control		Control
Sequence	Lv Hv	MH+[Da]	Ion Score	Exp Value	Ion Score	Exp Value	Ion Score	Exp Value	Ion Score	Exp Value	Ion Score	Exp Value	Ion Score	Exp Value	Ion Score	Exp Value	Ion Score	Exp Value
₃₂LLVVYPWTVR₄₁	-	1306.716			45	7.34E-03	45	7.52E-03	49	3.15E-03	41	2.04E-02	41	1.88E-02	41	2.09E-02	49	360E-03
₅₄SDDTAVYYNAR₅₄	Hv	1320.549	47	3.67E-03
₃₇ASGGTFSSYLVGWVR₅₁	Hv	1631.775			61	4.03E-04
₂₅ASQGISNFLAWYQK₃₈	Hv	1657.795			42	3.11E-02
₃₈LLIYAASGLQSGVPSR₅₃	Lv	1676.886			40	3.40E-02
₂₆TSGGTFSNYAISWVR₄₀	Hv	1706.791			44	1.63E-02
₉₀TDDTAVYYCSTELK₁₀₃	Hv	1710.747	38	4.75E-02
₆₆LLIYAAPSLQSGIPSR₃₁	Lv	1731.925					44	1.39E-02
₃₄LLIYAASILQTGVPSR₄₉	Lv	1747.925	60	3.73E-04
₇₂QYNASVSVPDSSGPER₈₆*	-	1780.797					62	2.18E-04							64	1 64E-04	63	1.67E-04
₂₄₄VVSVLTVLHQDWLGGK₂₅₉	-	1812.985	42	1.39E-02
₁₉₆VYADEVTHQGLSSPVTK₂₁₂	-	1875.923	77	1.27E-05	83	3.01E-06	81	4.70E-06	72	4.07E-05
₈₅LQQGYNATGFSQGGQFLR₁₀₂	-	2017.953											53	3.39E-03
₉₇AFDYWGQGTLVTVSSASTK₁₁₅	Hv	2063.004			92	4.51E-07
₁₀₈NFDHWGRGTLVTVSSASTK₁₂₆	Hv	2124.040			56	1.71E-03
₁₉₄HKVANEVTHQGLSSPVTK₂₁₂	-	2141.081	47	1.09E-02
₈₆GAPFDPWGQGTLVTVSSASTK₁₀₄	Hv	2167.042			41	4.56E-02
₁₀₁DTFDIWGQGTLVTVSSASTK₁₂₁	Hv	2174.040	51	5.63E-03
₉₃LFFGQPGWGQGTLVTVSSASTK₁₁₄	Hv	2330.172	43	2.77E-02
₃₅GLEWIGEINRSGATNYPSLK₅₅	Hv	2365.146	46	1.89E-02
₂₅ASQSVTNYLAWYQQKPGQAPR₄₅	Lv	2439.205			66	1.89E-03
₈₉KAASYGVDVWGQGTTVTVSSASTK₁₀₂	Hv	2461.185			42	5.09E-02
₂₃AGQSISSNYLAWYQQKPGQAPR₄₄	Lv	2496.232	59	8.56E-04
₉₇YSYGLFDSWGQGTLVTVSSASTK₁₁₉	Hv	2500.142			57	1.46E-03
₉₄RLGALGSIDDWGQGTLVTVSSASTK₁₁₈	Hv	2580.272	43	3.70E-02
₉₉WWSSAMDYWGQGTLVTVSSASTK₁₂₁	Hv	2625.163	48	1.02E-02
₈₉ANVAVAVANDYWGQGTLVTVSSASTK₁₁₄	Hv	2656.289	67	1.67E-04
₃₉QAPGQGGLEWMGGIIPIFGSTKYAQK₅₃	Hv	2723.396			63	2.56E-03

HIV, brain samples from individuals with HIV infection without encephalitis; HIV-E, brain samples from individuals with HIV infection and encephalitis; PSM, peptide spectrum match; Hv, heavy chain variable region; and Lv, light chain variable region on immunoglobulins. On the peptide sequences, nitrotyrosines and nitrohydroxytryptophans are shown in red, deamidated residues are indicated in green, carbamidomethylated cysteines are colored green, and the oxidized methionine is shown in purple. The peptide with an asterisk has N-terminus acetylation. The complete peptide identification information can be found in Supporting Information Table 4.

Table 1. Nitrated Peptides from the Anti-3-Nitrotyrosine Antibody–Agarose-Immunoprecipitated Brain Proteinsa.

Table 1. Nitrated Peptides from the Anti-3-Nitrotyrosine Antibody–Agarose-Immunoprecipitated Brain Proteins^a.