. Author manuscript; available in PMC: 2016 Jan 31.

Published in final edited form as: Am J Alzheimers Dis Other Demen. 2014 Jun 6;31(1):34–39. doi: 10.1177/1533317514537549

Table 1.

Characteristics of prior studies investigating the association of hearing loss and APOE-E4 allele status.

	Cohort	Analytic Sample	Study Objective	Findings^a
Kurniawan et al. (2012)	Leiden 85 Plus Study	435	Hearing Thresholds by APOE-E allele status	E4 (−/−) 56.1 dB Loss (n=6)	E4 (+/−) 51.0 dB Loss (n=89)	E4(+/+) 48.9 dB Loss (n=340)
O’Grady et al. (2007)	Convenience Sample	89	Observed vs expected allele frequencies by severity of hearing loss	No association of E4 Allele and hearing loss (n=18 E4 alleles)

E4 (−/−), Individuals with zero E4 alleles. E4 (−/+), individuals with one E4 allele. E4 (+/+), individuals with two E4 alleles