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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Cell Mol Life Sci. 2014 May 28;71(19):3767–3778. doi: 10.1007/s00018-014-1648-6

Figure 2. Roles of phospholipids in mitochondrial division, fusion and degradation.

Figure 2

During mitochondrial division, phospholipids help assemble Dnm1/Drp1 on the surface of mitochondria together with its receptor proteins. Upon stress, CL is externalized to the outer membrane and can promotes mitophagy and apoptosis. During mitochondrial fusion, dynamin-related GTPases and phospholipids work together. While Fzo1/mitofusin along with PA and LPA mediate outer membrane fusion, Mgm1/Opa1, CL and PE control inner membrane fusion.