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. Author manuscript; available in PMC: 2014 Sep 2.
Published in final edited form as: Yao Wu Shi Pin Fen Xi. 2013 Dec;21(4):S52–S58. doi: 10.1016/j.jfda.2013.09.034

Fig. 4.

Fig. 4

Activity of SOE against NNRTI mutant pseudovirus and a PI resistant strain. Serially diluted SOE was added to GHOST-CCR5 and GHOST-CXCR4 infected with NNRTI mutant pseudoviruses (K103N, Y188L and K103N/Y188L/G190A) and a PI resistant strain (PI-2840), respectively (A). Nevirapine (NVP) was included as control (B). All NNRTI mutant constructs were generated based on a molecular clone backbone, pNL4-3LucEnvVpr. The PI resistant strain (resistant to multiple anti-HIV protease drugs; 2840) carries L10R, M46I, L63P, V82T, and I84V. The luciferase level was measured 2 days PI. All results are means standard errors of the means from three independent experiments.