Table 2.
852A dose administration
| Patient | Total Doses Received |
Max Dose Received |
# of Max doses Received |
Dose Reduction |
Treatment Discontinued |
Reason |
|---|---|---|---|---|---|---|
| 1 | 24 | 1.2 | 14 | no | no | |
| 2 | 12 | 1.2 | 5 | yes | yes | disease progression |
| 3 | 9 | 1.2 | 3 | no | yes | disease progression |
| 4 | 6 | 1 | 2 | no | yes | nausea/vomiting |
| 5 | 1 | 0.6 | 1 | no | yes | EF-15% |
| 6 | 10 | 1.2 | 4 | no | yes | fatigue |
| 7 | 5 | 1 | 1 | no | yes | disease progression |
| 8 | 24 | 1.2 | 18 | no | no | |
| 9 | 12 | 1.2 | 6 | no | yes | disease progression |
| 10 | 37 | 1.2 | 31 | no | during second course | anorexia, nausea/vomiting |
| 11 | 24 | 1.2 | 2 | yes | no | |
| 12 | 2 | 0.6 | 2 | no | yes | non-ST elevated MI |
| 13 | 14 | 1.2 | 8 | no | yes | disease progression |
| 14 | 0 | DOD before first dose |
DOD=Dead of Disease