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Serum levels in naïve ELL2loxp/loxp CD19cre/+ mice are reduced with both exon 1 and exon 3 deletions. Control mice with either ELL2loxp/loxp CD19+/+ or ELL2+/+ CD19cre/+ (filled symbols, designated wt) and the ELL2 loxp/loxp CD19 cre/+ mice (open symbols, designated cKO) were bled at 7, 12 and 17 weeks. Serum was analyzed by ELISA for the indicated isotypes. P= 0.05 (*), 0.01 (**), or 0.001 (***) as indicated on graphs.
