Table 3.
gene | Control no LPS | Control 4d LPS | cKO no LPS | cKO 4d. LPS | control/cKO 4d. LPS |
---|---|---|---|---|---|
AFF1 | 3 | 9 | 0.6 | 5 | 1.8 |
AICDA | 0.6 | 33 | 1.8 | 21.3 | 1.6 |
ATF6 | 60 | 320 | 64 | 155 | 2.1 |
Bcl6 | 1.3 | 5.2 | 1.3 | 2 | 2.6 |
BiP | 400 | 1400 | 432 | 308 | 4.6 |
Blimp-1 | 0.5 | 48.7 | 1.0 | 40.1 | 1.2 |
BRD4 | 100 | 190 | 75 | 80 | 2.4 |
Cebp-β | 87 | 43 | 90 | 27 | 1.6 |
CstF64 | 1.5 | 7 | 2 | 3 | 2.3 |
Cyclin B2 | 15 | 65 | 15 | 8 | 8.1 |
Eaf1 | 1.8 | 6.6 | 2 | 4 | 1.7 |
Eaf2 | 7 | 55 | 2 | 35 | 1.6 |
ELL3 | 37 | 4 | 50 | 3 | 1.3 |
Hif1a | 33 | 22 | 25 | 22 | 1.0 |
Hsp40 | 40 | 40 | 38 | 50 | 0.8 |
Igh mb | 3000 | 2900 | 2200 | 6800 | 0.4 |
Igh sec | 5400 | 45,000 | 2600 | 1200 | 37.5 |
IRE1 | 20 | 270 | 20 | 174 | 1.6 |
IRF4 | 1.8 | 21.2 | 1.7 | 21.3 | 1 |
NF-kb p50 | 19 | 22 | 22 | 18 | 1.2 |
NF-kb p65 | 25 | 18 | 6 | 13 | 1.4 |
Pax5 | 36 | 57 | 35 | 45 | 1.3 |
PCNA | 70 | 250 | 150 | 300 | 0.8 |
Sup5H | 4 | 8.5 | 4 | 6.5 | 1.3 |
XBP1 Total | 70 | 405 | 71 | 100 | 4.0 |
XBP1 spliced | 4 | 70 | 3 | 3 | 23.3 |
S.E.M. less than 5% in all cases, not indicated for clarity; n> 6 mice each class, exon 1 and exon 3.