Table 2.

Mean differences in the inflammatory markers according to quartiles of daytime, nighttime and 24 h heart rate

	HR quartiles				P value#
	1st (n=96) Reference	2nd (n=90)	3rd (n=96)	4th (n=86)
Daytime HR, beats/min	61±5	70±2	77±2	86±5
Leukocyte count • 103/μL	5.6±0.14	0.1±0.02	0.4±0.06	0.7±0.07*	0.02
Platelet count • 103/μL	223±5.8	7±−0.7	28±0.1*	23±0.1*	0.003
CRP, mg/L	2.3±0.34	0.3±−0.02	1.4±0.17	0.6±0.03	0.07
25[OH]D, ng/mL	31.1±1.23	−1.9±−0.11	−2.7±−0.09	−1.7±−0.05	0.42
Nighttime HR, beats/min	53±4	61±2	67±2	76±5
Leukocyte count • 103/μL	5.5±0.14	0.3±0.02	0.3±0.01	1.2±0.07*†‡	<0.001
Platelet count • 103/μL	226±5.6	7±0.1	15±0.1	25±1.8*	0.03
CRP, mg/L	1.9±0.26	1.0±0.16	0.8±−0.01	1.9±0.29*	0.005
25[OH]D, ng/mL	32.4±1.19	−3.9±−0.02	−2.6±−0.01	−4.8±−0.04*	0.02
24 h HR, beats/min	60±4	68±2	74±2	84±5
Leukocyte count • 103/μL	5.5±0.13	0.3±0.03	0.5±0.03	0.8±0.08*	0.01
Platelet count • 103/μL	222±6.0	12±−0.7	27±−0.1*	24±1.3*	0.007
CRP, mg/L	2.3±0.35	0.2±−0.04	1.2±0.08	0.6±0.04	0.09
25[OH]D, ng/mL	31.8±1.15	−2.5±0.16	−3.4±−0.12	−2.8±0.07	0.16

Differences shown for inflammatory markers are versus the first quartile of heart rate measures (reference). Values are reported as mean±SD for heart rate measures and mean±SE for the inflammatory markers.

P values were determined using ANOVA.

^*P<0.05 versus the first quartile;

^†P<0.05 versus the second quartile;

^‡P<0.05 versus the third quartile.

Abbreviations as in Table 1.