Skip to main content
. Author manuscript; available in PMC: 2015 Jan 6.
Published in final edited form as: J Pathol. 2015 Jan;235(2):185–195. doi: 10.1002/path.4454

Figure 2.

Figure 2

Model of an infected alveolus in the lung. Type I and type II pneumocytes make up the alveolar walls, resident alveolar macrophages and pulmonary surfactant exist in the airspace (A). In the acute phase of SARS-CoV infection (B) type I and type II pneumocytes are infected and secrete inflammatory cytokines while surfactant levels decrease. During the late stage/tissue damage portion of viral infection viral titres decrease while airway debris, pulmonary oedema and hyaline membrane formation all impede respiration (C).