Table 1.
MDCK cells | PC1 variant expressed | Description |
---|---|---|
MDCKPC1WT | PC1WT | Full-length wild-type PC1 with a C-terminal FLAG tag |
MDCKPC1–2M | PC12M | Full-length PC1 with a C-terminal FLAG tag, containing amino acid substitutions at L4219P and A4222P within the coiled-coil domain |
MDCKPC1-R/X | PC1R/X | PC1 terminating at R4218X with a C-terminal FLAG tag before the stop codon |
MDCKPC1V | PC1V | Full-length PC1 with a C-terminal FLAG tag, containing amino acid substitution T3041V at GPS cleavage site |