Table I.
Effect of PCB126 and PCB153 on the organ and tissue weight.
| Group/ Implants | Duration of study (days) | Body wt. (g) | Liver (mg/g bw) | Lung (mg/g bw) | Kidney (g) | Thymus (mg) | Ovary (mg) | Mammary (g) |
|---|---|---|---|---|---|---|---|---|
| Untreated control | 15 | 179 ± 3.6 | 42.6 ± 1.2 | 6.0 ± 0.3 | 1.4 ± 0.1 | 359 ± 6 | 111 ± 9 | 3.1 ± 0.3 |
| Sham Implants | 15 | 178 ± 10.4 | 40.9 ± 0.8 | 6.4 ± 1.0 | 1.4 ± 0.1 | 323 ± 2 | 112 ± 16 | 3.5 ± 0.2 |
| PCB 153 | 15 | 181 ± 11.7 | 40.5 ± 3.5 | 5.8 ± 0.5 | 1.4 ± 0.1 | 358 ± 3 | 128 ± 17 | 3.8 ± 0.6 |
| PCB 126 | 15 | 177 ± 4.8 | *55.2 ± 4.4 | 8.2 ± 2.4 | 1.3 ± 0.1 | *222 ± 3 | 93 ± 16 | 2.9 ± 0.6 |
| PCB126 + PCB153 | 6 | 156 ± 3.9 | *53.2 ± 4.4 | 6.5 ± 0.5 | 1.3 ± 0.2 | ***270 ± 3 | 80 ± 13 | 2.6 ± 0.2 |
| PCB126 + PCB153 | 15 | 169 ± 5.9 | *57.9 ± 3.4 | 7.7 ± 1.5 | 1.4 ± 0.2 | ***248 ± 6 | 93 ± 14 | 3.0 ± 0.2 |
| PCB126 + PCB153 | 45 | 213 ± 7.3 | *48.3 ± 2.5 | 6.6 ± 0.4 | 1.5 ± 0.1 | ***110 ± 1 | 105 ± 9 | 3.5 ± 0.7 |
*
p < 0.05, significantly different from the 15 day untreated control, animals.
***
p ± 0.001. Data shown is average ± SD of four significantly different from the 15 day untreated control, animals.