Table 1.
Select sample of non-randomized studies
Study | Participants | Age | Follow up time | Results for motor success |
Results for sen- sory success |
Study investiga- tors’ conclusions |
---|---|---|---|---|---|---|
Dadeya 2001 | Group 1 (50 par- tic- ipants): surgery AFTER comple- tion of ambly- opia therapy Group 2 (50 par- tic- ipants): surgery BEFORE com- pletion of ambly- opia therapy |
< 9 years | 3 months after surgery |
Group 1: 84% Group 2: 75% |
Group 1: 55% Group 2: 50% |
“There was no sig- nificant differ- ence in motor suc- cess (84% vs 75%) and sensory suc- cess (55% vs 50%) whether amblyopia was fully treated or partially treated.” |
Lam 1993 | Group 1 (26 par- tic- ipants): surgery AFTER comple- tion of ambly- opia therapy Group 2 (21 par- tic- ipants): surgery BEFORE com- pletion of ambly- opia therapy |
< 8 years | 6 months after surgery |
Group 1: 14/26 (54%) Group 2: 12/21 (57%) |
Group 1: 8/14 (57%) Group 2: 5/12 (42%) |
“There was no sig- nificant difference detected in motor or sensory outcome whether amblyopia was fully or only partially treated be- fore surgery.” It was noted that five of the 21 patients who had surgery before amblyopia therapy was complete re- portedly had spon- taneous re- versal of amblyopia after surgery |
Weakley 1997 | Group 1 (51 par- ticipants) : surgery in chil- dren with no am- blyopia, includ- ing those previ- ously treated for amblyopia Group 2 (51 par- tic- ipants): surgery BEFORE com- pletion of ambly- opia therapy |
< 9 years | 4 to 6 weeks after surgery |
Group 1: 43/51 (84%) Group 2: 39/51 (76%) |
Not assessed | “The presence of mild or moderate amblyopia does not appear to have an influence on surgi- cal outcome for pa- tients with acquired esotropia. The effect of am- blyopia on sensory outcome was not studied as most patients were too young for re- liable sensory test- ing” |