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. Author manuscript; available in PMC: 2015 Oct 15.
Published in final edited form as: Cochrane Database Syst Rev. 2014 Oct 15;10:CD009272. doi: 10.1002/14651858.CD009272.pub2

Table 1.

Select sample of non-randomized studies

Study Participants Age Follow up time Results for motor
success
Results for sen-
sory success
Study investiga-
tors’ conclusions
Dadeya 2001 Group 1 (50 par-
tic-
ipants): surgery
AFTER comple-
tion of ambly-
opia therapy
Group 2 (50 par-
tic-
ipants): surgery
BEFORE com-
pletion of ambly-
opia therapy
< 9 years 3 months after
surgery
Group 1: 84%
Group 2: 75%
Group 1: 55%
Group 2: 50%
“There was no sig-
nificant differ-
ence in motor suc-
cess (84% vs 75%)
and sensory suc-
cess (55% vs 50%)
whether amblyopia
was fully treated or
partially treated.”
Lam 1993 Group 1 (26 par-
tic-
ipants): surgery
AFTER comple-
tion of ambly-
opia therapy
Group 2 (21 par-
tic-
ipants): surgery
BEFORE com-
pletion of ambly-
opia therapy
< 8 years 6 months after
surgery
Group 1: 14/26
(54%)
Group 2: 12/21
(57%)
Group 1: 8/14
(57%)
Group 2: 5/12
(42%)
“There was no sig-
nificant difference
detected in motor
or sensory outcome
whether amblyopia
was fully or only
partially treated be-
fore surgery.”
It was
noted that five of
the 21 patients who
had surgery before
amblyopia therapy
was complete re-
portedly had spon-
taneous re-
versal of amblyopia
after surgery
Weakley 1997 Group 1 (51 par-
ticipants)
: surgery in chil-
dren with no am-
blyopia, includ-
ing those previ-
ously treated for
amblyopia
Group 2 (51 par-
tic-
ipants): surgery
BEFORE com-
pletion of ambly-
opia therapy
< 9 years 4 to 6 weeks after
surgery
Group 1: 43/51
(84%)
Group 2: 39/51
(76%)
Not assessed “The presence of
mild or moderate
amblyopia does not
appear to have an
influence on surgi-
cal outcome for pa-
tients with
acquired esotropia.
The effect of am-
blyopia on sensory
outcome
was not studied as
most patients were
too young for re-
liable sensory test-
ing”