TABLE I.
LTLE | RTLE | Controls | |
---|---|---|---|
N | 21 | 23 | 28 |
Age | 42.5±13.6 | 36.4±14.5 | 39.3±13.3 |
Gender F/M | 15/7 | 10/13 | 21/7 |
Intracranial Volume (Liters) | 1.35±0.23 | 1.48±0.27 | 1.52±0.18 |
Edinburgh Handedness | 87±44 | 78±57 | 76±53 |
W/o Right Arcuate | 13/8 | 19/4 | 25/3 |
Full Scale IQ | 91±13.8 | 96±10.4 | n/a |
Age at epilepsy onset | 19±16.1 | 22±12.1 | n/a |
Duration of Epilepsy | 24±19.1 | 15±12.3 | n/a |
Seizure Types (no. of patients) | 13 – CPS only 2 – CPS + GTCS 1 – SPS only 1 – CPS w/2° GTCS 3 – CPS + SPS 0 – CPS w/2° GTCS + SPS |
12 – CPS only 4 – CPS + GTCS 0 – SPS only 3 – CPS w/2° GTCS 3 – CPS + SPS 1 – CPS w/2° GTCS + SPS |
|
MTS/non-MTS (no. of patients) | 11/10 | 9/14 | n/a |
Sugery | 14 (67%) 12 – ATL 1 – laser ablation 1 – gamma knife |
14 (61%) 14 – ATL |
|
Seizure-free post-surgery | 12 (86%) range: 14–72 months post-op |
9 (64%) range: 8–48 months post-op |
|
Medication (no. of patients) | 4 – Carbamazepine 1 – Depakote 2 – Lacosamide 7 – Lamotrigine 10 – Levetiracet 1 – Oxcarbazepine 2 – Phenobarbital 3 – Topiramate 2 – Zonisamide 5 – Other |
4 – Carbamazepine 3 – Depakote 5 – Lacosamide 4 – Lamotrigine 12 – Levetiracet. 4 – Oxcarbazepine 1 – Phenobarbital 3 – Topiramate 3 – Zonisamide 6 – Other |
Abbreviations: MTS=mesial temporal sclerosis, CPS=complex partial seizures, GTCS=generalized tonic-clinic seizures, SPS=simple partial sizures, w/2° GTCS=with secondary generalization.