TABLE II.
Fractional anisotropy values of the nine tracts, followed by statistical comparisons between groups after accounting for gender and intracranial volume
| GROUP | Main ANCOVA (F-test) | LTLE vs. Controls (95% CI) | RTLE vs. Controls (95% CI) | LTLE vs. RTLE (95% CI) | |||
|---|---|---|---|---|---|---|---|
| Controls (FA) | Left TLE (FA) | Right TLE (FA) | |||||
| Fornix | .37±.03 | .34±.04 | .35±.03 | F[2.67]=3.1 p=.052 ηp2=.09 |
n.s. | n.s. | n.s. |
| Parahip. Left | .40±.03 | .36±.04 | .39±.02 | F[2.67]=5.52* p=.006 ηp2=.14 |
[−.051, −.012] p=.002 ηp2=.14 |
n.s. | n.s. |
| Parahip. Right | .38±.02 | .35±.03 | .36±.03 | F[2.67]=7.39** p=.001 ηp2=.18 |
[−.043, −.012] p=.001 ηp2=.16 |
[−.035, −.007] p=.005 ηp2=.11 |
n.s. |
| Arcuate Left | .48±.02 | .44±.04 | .45±.03 | F[2.67]=5.8** p=.005 ηp2=.15 |
[−.042, −.009] p=.003 ηp2=.12 |
n.s. | n.s. |
| Arcuate Right | .45±.03 | .44±.03 | .43±.04 | F[2.67]=1.6 p=.204 ηp2=.06 |
n.s. | n.s. | n.s. |
| Frontopar. Left | .43±.02 | .41±.03 | .42±.02 | F[2.67]=5.4* p=.007 ηp2=.14 |
[−.034, −.007] p=.003 ηp2=.12 |
n.s. | n.s. |
| Frontopar. Right | .45±.02 | .42±.03 | .42±.03 | F[2.67]=7.6** p=.001 ηp2=.19 |
[−.040, −.008] p=.003 ηp2=.12 |
[−.041, −.012] p=.001 ηp2=.16 |
n.s. |
| Uncinate Left | .41±.02 | .39±.03 | .40±.03 | F[2.67]=3.0 p=.058 ηp2=.08 |
n.s. | n.s. | n.s. |
| Uncinate Right | .42±.02 | .38±.04 | .39±.03 | F[2.67]=11.2** p<.001 ηp2=.26 |
[−.047, −.014] p<.001 ηp2=.17 |
[−.049, −.019] p<.001 ηp2=.23 |
n.s. |
| Average FA (all tracts) | .43±.02 | .40±.03 | .41±.02 | F[2.67]=8.1** p=.001 ηp2 =.19 |
[−.038, −.010] p=.001 ηp2 =.16 |
[−.034,. −.008] p=.001 ηp2=.14 |
n.s. |
FA values for each tract (± standard deviation) and ANCOVA results for the “group” factor after accounting for gender and intracranial volume as covariates. Planned comparisons indicate 95% confidence interval, p-value, and effect size (ηp2=partial eta squared, n.s.=non significant at α=.0056).
*
ANCOVA shows statistical trend (.006<p<.007).
**
ANCOVA is significant at α<.0056.