TABLE 4.

Relation of prenatal alcohol exposure and other predictors to the DTI and physical outcome measures in the WM-ROIs in each of the networks.

		FA			MD			AD			PD
Network	Pred.	βmed	F (dfN, dfD)	p	βmed	F (dfN, dfD)	p	βmed	F (dfN, dfD)	p	βmed	F (dfN, dfD)	p
CCCR
	alc				−0.70	8.6 (1, 14)	0.011*	−0.72	14.0 (1, 14)	0.002*
	clg							−0.27	2.5 (6, 9)	0.101	0.47	3.5 (1, 14)	0.083
	mat. age				0.56	5.5 (1, 14)	0.034*	0.53	6.3 (1, 14)	0.025*
L-PROJ
	alc				−0.41	3.9 (10, 140)	0.000***	−0.52	4.1 (10, 140)	0.000***
	clg	0.12	4.2 (11, 4)	0.091							0.52	4.0 (1, 14)	0.066
	mat. age				0.37	4.4 (1, 14)	0.056	0.44	6.5 (1, 14)	0.023*
R-PROJ
	alc				−0.41	1.9 (12, 168)	0.035*	−0.45	2.7 (12, 168)	0.002**
	clg										0.48	3.4 (1, 14)	0.085
	age	0.33	8.6 (13, 2)	0.109	−0.41	5.8 (1, 14)	0.031*	−0.39	5.3 (1, 14)	0.038*
	mat. age	−0.16	9.2 (13, 2)	0.103
	sex				−0.20	4.3 (1, 14)	0.056	−0.39	5.9 (1, 14)	0.029*
L-ASSOC
	alc				−0.65	6.0 (7, 8)	0.011*	−0.66	8.1 (1, 14)	0.013*
	clg										0.49	3.6 (1, 14)	0.080
	age							−0.16	2.5 (6, 84)	0.030*
	mat. age				0.44	3.8 (1, 14)	0.071	0.43	4.7 (1, 14)	0.048*
R-ASSOC
	alc	0.23	1.8 (7, 98)	0.090	−0.62	10.2 (1, 14)	0.007**	−0.67	14.1 (1, 14)	0.002**
	clg							−0.29	3.9 (1, 14)	0.068	0.5	3.5 (1, 14)	0.082
	age							−0.05	5.5 (8, 7)	0.018*	−0.22	5.6 (8, 7)	0.018*
	mat. age	−0.10	2.3 (7, 98)	0.035*	0.43	4.5 (1, 14)	0.053	0.40	5.7 (1, 14)	0.032*
	sex	0.18	2.5 (7, 98)	0.020*							0.13	2.0 (7, 98)	0.068

F-values are shown with final degrees of freedom of numerator (df_N) and denominator (df_D). Median standardized β-values were calculated from the additional multivariate regressions of each network’s individual WM-ROIs (Sec. 3.3). Only predictors exhibiting effects at p≤0.10 are shown.

^*p<0.05;

^**p<0.01;

^***p<0.001.

alc = frequency of maternal drinking; age = infant age since conception; sex: male=1, female = 2; cig = maternal smoking (cig/day); mat. age = maternal age at