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(A) Deconvoluted mass spectra of deuterated intact Mb from formulations MbT (solid line) and MbS (dashed line) following 144 h of ssHDX. The deconvoluted mass spectrum of undeuterated intact Mb is also shown (dotted line). (B) ssHDX kinetics for intact Mb in formulations MbT (solid line) and MbS (dashed line). The time course of ssHDX was fitted to an equation for two phase exponential association using Graph Pad Prism software version 5 (n = 3, ± SD).
