Table 4.

Any-Grade AEs Reported in > 15% of Patients Overall or Grade ≥ 3 AEs Reported in > 5% of Patients Overall

	Ovarian (n = 193)				Breast (n = 62)				Pancreas (n = 23)				Prostate (n = 8)				Other (n = 12)				Total (N = 298)
	Any Grade		Grade ≥ 3		Any Grade		Grade ≥ 3		Any Grade		Grade ≥ 3		Any Grade		Grade ≥ 3		Any Grade		Grade ≥ 3		Any Grade		Grade ≥ 3
AE	No.	%	No.	%	No.	%	No.	%	No.	%	No.	%	No.	%	No.	%	No.	%	No.	%	No.	%	No.	%
Fatigue	116	60.1	12	6.2	30	48.4	3	4.8	17	73.9	3	13.0	1	12.5	0	0.0	12	100.0	1	8.3	176	59.1	19	6.4
Nausea	119	61.7	1	0.5	33	53.2	0	0.0	11	47.8	0	0.0	3	37.5	0	0.0	10	83.3	0	0.0	176	59.1	1	0.3
Vomiting	75	38.9	5	2.6	21	33.9	1	1.6	9	39.1	1	4.3	0	0.0	0	0.0	6	50.0	0	0.0	111	37.2	7	2.3
Anemia	62	32.1	36	18.7	16	25.8	9	14.5	9	39.1	4	17.4	5	62.5	1	12.5	6	50.0	2	16.7	98	32.9	52	17.4
Diarrhea	56	29.0	3	1.6	11	17.7	1	1.6	7	30.4	0	0.0	3	37.5	0	0.0	4	33.3	0	0.0	81	27.2	4	1.3
Abdominal pain	58	30.1	14	7.3	5	8.1	1	1.6	7	30.4	1	4.3	0	0.0	0	0.0	7	58.3	1	8.3	77	25.8	17	5.7
Decreased appetite	36	18.7	1	0.5	17	27.4	0	0.0	4	17.4	0	0.0	2	25.0	0	0.0	3	25.0	0	0.0	62	20.8	1	0.3
Dyspepsia	38	19.7	0	0.0	9	14.5	0	0.0	2	8.7	0	0.0	0	0.0	0	0.0	3	25.0	0	0.0	52	17.4	0	0.0
Headache	32	16.6	0	0.0	14	22.6	1	1.6	1	4.3	0	0.0	0	0.0	0	0.0	1	8.3	0	0.0	48	16.1	1	0.3
Dysgeusia	39	20.2	0	0.0	4	6.5	0	0.0	1	4.3	0	0.0	0	0.0	0	0.0	3	25.0	0	0.0	47	15.8	0	0.0

Abbreviation: AE, adverse event.