Table 1. Post-translational modifications of the protein involved in mitochondrial dynamics.

List of important post-translational modifications of the key molecules of mitochondrial dynamics and their upstream modulators with its final consequences on cell physiology

Protein	Modification	Induced by	Effect	Ref
Drp-1	Phosphorylation	CDK1	Enhanced Mitochondrial Fission	[50]
	(S616)	Erk1/2	Enhanced Mitochondrial Fission	[52]
		PKCδ	Enhanced Mitochondrial Fission	[142]
		CDK5	Reduced Mitochondrial Fission	[59]
	Phosphorylation S637	PKA,	Reduced Mitochondrial Fission	[53]
		CaMK1α	Enhanced Mitochondrial Fission	[57]
		ROCK1	Enhanced Mitochondrial Fission	[58]
	Dephosphorylation S637	Calcineurin	Enhanced Mitochondrial Fission	[56]
	S-Nitrosylation C644	Nitric oxide	Enhanced Mitochondrial Fission	[60]
	Sumoylation	MAPL	Enhanced Mitochondrial Fission	[61]
	Desumoylation	SENP5	Reduced Mitochondrial Fission Degradation	[62]
	Ubiquitination	MITOL	Degradation	[64]
		Parkin	Degradation	[79]
Fis-1	Ubiquitination	MITOL	Degradation	[64]
Mfn-1	Ubiquitination	Parkin	Degradation	[39]
	Ubiquitination	MARCH5	Degradation	[143]
Mfn-2	Ubiquitination	Parkin	Degradation	[39]
	Phosphorylation T111, S442	PINK1	Parkin recruitment	[74]
Opa-1	Acetylation K926/931	Stress	Reduced GTPase activity	[34]
	De-acetylation K926/931	SIRT3	High GTPase activity	[34]