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. Author manuscript; available in PMC: 2015 Apr 6.
Published in final edited form as: Med Care. 2015 Apr;53(4):332–337. doi: 10.1097/MLR.0000000000000328

Table 2.

Estimated Risk Ratios of Being Adherent (PDC≥80%) to Medications in Therapeutic Category.

ACEI/ARB (n=83,044) ORAL DM (n=54,488) STATINS (n=90,020)
Age (ref: 65-69)
    70-74 0.99 1.00 1.01
    75-79 0.99* 0.98** 1.01
    80-84 0.97*** 0.97*** 1.01
    85+ 0.97*** 0.95*** 1.00
Female 1.00 0.98*** 0.96***
Race/Ethnicity (ref: White)
    Hispanic 0.97*** 0.98** 0.95***
    American Indian/Alaska Native 0.99 0.96 0.95
    Asian 1.00 1.01* 1.00
    Native Hawaiian/Pacific Islander 0.92** 0.98 0.93*
    Black 0.96*** 0.93*** 0.91***
    Missing Race 1.02*** 1.02** 1.01
Census Block Group Median Household Income (ref: <$30,000)
    $30,000-$49,999 1.00 1.00 1.01
    $50,000-$69,999 1.00 1.00 1.01
    $70,000-$89,999 1.00 1.01 1.02*
    $90,000+ 1.00 1.00 1.02*
Census Block Group Percentage of Adults with a Bachelor's Degree or Higher Degree (ref: <15%)
    15-24% 1.00 1.00 1.00
    25-49% 1.01 1.01 1.01
    50%+ 1.00 1.00 1.00
Number of Medications at Study Start 1.01*** 1.02*** 1.02***
Mean Days Supply of Drugs in Therapeutic Category in 2010 (ref: <31)
    31-60 1.12*** 1.23*** 1.11***
    61-90 1.35*** 1.48*** 1.47***
    >90 1.61*** 1.61*** 1.61***
Percentage of Drugs in Therapeutic Category Refilled Via Mail Order Pharmacy in 2010 (ref: 0%)
    1%-50% 1.01 1.01 1.01
    51%-100% 1.07*** 1.06*** 1.07***
Generic Drug Co-Payment for 30 Day Supply in 2010 (ref: >$10)
    $0-$10 1.02** 1.02** 1.02**
Annual Individual Out-of-Pocket Maximum in January 2010 (ref: >$2,000)
    $0-$2,000 1.02*** 1.01** 1.02***
Interaction of: Percentage Refilled via Mail Order Pharmacy × Race
    51%-100% × Black 1.02 1.05* 1.05**
    51%-100% × Hispanic 1.03** 1.01 1.04**
*

Statistically significant at p<0.05

**

p<0.01

***

p<0.001

Notes: (1) Models adjusted for HMO site and whether patient was enrolled in health plan for all 12 months of 2010; (2) 3,076, 2,141, and 3,256 observations with missing values for census block group variables and generic drug co-payment excluded from ACEI/ARB, ORAL DM, and STATINS regressions, respectively.