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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Brain Pathol. 2014 Dec 5;25(5):575–586. doi: 10.1111/bpa.12217

Table 4.

Additional therapy and follow-up.

First diagnosis
PXA (n = 51) PXA-AF (n = 23)
Postoperative therapy, n (%)
 Any type 17 (33.3%) 18 (78.3%)
 Radiotherapy (RT) only 5 (9.8%) 3 (13.0%)
 Radiosurgery (RS) only 1 (2.0%) 0
 Chemotherapy +/− RT/RS 11 (21.6%) 14 (60.9%)
 RT + RS 0 1 (4.3%)
Median follow-up, years (range) 11.2 (0.6–31.9) 4.0 (0.1–22.9)
Recurrence, n 21 11
Outcome, n
 Alive 20 6 (0.1–25.4 years)*
 Alive with disease 7 3 (0.8–20.0 years)*
 Died 2 2 (4.0–20.5 years)*
 Died of disease 6 8 (0.8–27.7 years)*
 No evidence of disease 16 4 (0.6–31.9 years)*
5-year survival % (95% CI)
Recurrence-free 70.9% (58.0–83.8) 48.9% (26.5–71.3) P = 0.092
Overall 90.4% (81.5–99.4) 57.1% (34.2–80.0) P = 0.0003
*

Total available follow-up.

PXA = pleomorphic xanthoastrocytoma; PXA-AF = pleomorphic xanthoastrocytoma with anaplastic features.