Table 4.
Additional therapy and follow-up.
First diagnosis
|
|||
---|---|---|---|
PXA (n = 51) | PXA-AF (n = 23) | ||
Postoperative therapy, n (%) | — | — | — |
Any type | 17 (33.3%) | 18 (78.3%) | — |
Radiotherapy (RT) only | 5 (9.8%) | 3 (13.0%) | — |
Radiosurgery (RS) only | 1 (2.0%) | 0 | — |
Chemotherapy +/− RT/RS | 11 (21.6%) | 14 (60.9%) | — |
RT + RS | 0 | 1 (4.3%) | — |
Median follow-up, years (range) | 11.2 (0.6–31.9) | 4.0 (0.1–22.9) | — |
Recurrence, n | 21 | 11 | — |
Outcome, n | — | — | — |
Alive | 20 | 6 | (0.1–25.4 years)* |
Alive with disease | 7 | 3 | (0.8–20.0 years)* |
Died | 2 | 2 | (4.0–20.5 years)* |
Died of disease | 6 | 8 | (0.8–27.7 years)* |
No evidence of disease | 16 | 4 | (0.6–31.9 years)* |
5-year survival % (95% CI) | — | — | — |
Recurrence-free | 70.9% (58.0–83.8) | 48.9% (26.5–71.3) | P = 0.092 |
Overall | 90.4% (81.5–99.4) | 57.1% (34.2–80.0) | P = 0.0003 |
Total available follow-up.
PXA = pleomorphic xanthoastrocytoma; PXA-AF = pleomorphic xanthoastrocytoma with anaplastic features.