Skip to main content
. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Hum Brain Mapp. 2015 Feb 20;36(6):2187–2206. doi: 10.1002/hbm.22764

Figure 6.

Figure 6

Category-specific hemispheric asymmetry of VOTC RSFC with OTHER-TOOL and OTHER-ANIMAL regions. (A–E) Plots indicate the degree of hemispheric asymmetry (leftward vs. rightward) of RSFC of homologous VOTC regions with OTHER category-preferential regions; positive values (blue bars) indicate stronger RSFC with the left VOTC-homologue; negative values (yellow bars) indicate stronger RSFC with the right VOTC-homologue; gray bars indicate no significant difference between right and left VOTC RSFC. (A–C) Hypothetical pattern of results expected if there were (A) only a main effect of category with no hemispheric asymmetry: mean RSFC of both the medFG and latFG with both OTHER-TOOL and OTHER-ANIMAL ROIs would not differ across hemispheres; (B) only a main effect of hemisphere (e.g., RSFC: ipsilateral > contralateral), with no category effect: the left lateralized OTHER-TOOL regions would show stronger mean RSFC with both the left medFG and left latFG relative to their respective homologous regions in the right VOTC, while the right lateralized OTHER-ANIMAL regions would show stronger RSFC with both the right latFG and right medFG relative to their respective homologous regions in the left VOTC; or (C) the predicted VOTC-hemisphere (left vs. right) by category (OTHER-TOOL regions vs. OTHER-ANIMAL regions) interaction for both the medFG and latFG: the OTHER-TOOL regions would show stronger mean RSFC with the left medFG than the right medFG, but the OTHER-ANIMAL regions would show no difference with the left vs. right medFG; conversely, the OTHER-ANIMAL regions would show stronger mean RSFC with the right latFG than the left latFG, but the OTHER-TOOL regions would show no difference with the right vs. left latFG. (D) Group-level analysis: Actual results mirrored the hypothetical predicted results (C), demonstrating leftward asymmetry of medFG RSFC with only OTHER-TOOL regions, but not with OTHER-ANIMAL regions, and conversely, rightward asymmetry of latFG RSFC with only OTHER-ANIMAL regions, but not with OTHER-TOOL regions. (E) Individual ROI analyses: there was leftward asymmetry of RSFC of the medFG with all of the individual TOOL ROIs (IPS, IPL, pMTG, vPM) but no asymmetry of RSFC with any of the ANIMAL ROIs. Conversely, there was rightward asymmetry of RSFC of the latFG with three of four ANIMAL ROIs (OFA, EBA, and AMG) but no asymmetry of RSFC with any of the TOOL ROIs. o-tool, OTHER-TOOL regions; o-animal, OTHER-ANIMAL regions; ** P < 0.01; * P < 0.05; n.s., not significant. Braces indicate significant VOTC-hemisphere by category interactions; Error bars represent between-subjects s.e.m.