Table 2.

Brain areas that showed significant differences between Complex and Simple arithmetic problems in the DD and TD groups.

Region	BA	# of voxels	Peak Z-score	Peak MNI coordinates
				x	y	z
TD group
Complex > Simple
L IPS	7	440	3.22	−24	−82	48
L Precuneus	19		3.04	−20	−84	48
L SPL	7		2.79	−28	−70	50
R Precuneus	7	573	3.22	2	−68	56
L Precuneus	7		2.87	−4	−66	44
R IPS/SPL	7	481	3.15	36	−62	58
R SMG	40		3.08	44	−50	58
L/R Fusiform gyrus, L	17, 18	5426	4.76	−22	−94	−18
Cerebellum, L ITG	37
L Visual cortex	18		4.66	−22	−102	−4
L LOC	19		3.81	−36	−92	−14
R MFG	9	7331	4.46	50	28	26
R Frontopolar cortex	11		3.98	26	60	−4
R MFG	8		3.81	8	32	44
R PMC	6		3.81	54	12	44
L MFG	9	3061	3.77	−54	22	32
L MFG	10		3.68	−46	52	4
L MFG	47		3.47	−36	42	4
L PMC	6	134	3.08	−28	2	60
L Insula	13	176	2.90	−32	18	2
L Mid-cingulate gyrus	23	402	2.90	2	−10	34
L Posterior-cingulate gyrus	31		2.74	−2	−30	32
R Anterior-cingulate	24		2.58	4	6	30
Brain Stem		182	3.44	0	−14	−8
Simple > Complex
None
DD group
Complex > Simple
None
Simple > Complex
L vmPFC	11	350	3.01	−8	38	−6
R vmPFC	10		2.66	6	44	−6
R Caudate		143	3.28	2	12	−6
R MTG	37	132	2.72	60	−60	18

IPS = intraparietal sulcus; ITG = inferior temporal gyrus; LOC = lateral occipital cortex; MFG = middle frontal gyrus; MTG = middle temporal gyrus; PMC = premotor cortex; SMG = supramarginal gyrus; SPL = superior parietal lobule; vmPFC = ventromedial prefrontal cortex.