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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Radiology. 2014 Nov 7;274(3):752–763. doi: 10.1148/radiol.14132871

Table 2.

Description of employed metrics, where A= algorithm-dependent deformed ROI volume, R= reference anatomic manually segmented ROI volume.

Metric Symbolic Expression Description Full agreement
Volume Overlap
VO=|AR||R|
The portion of the reference ROI which is overlapped by the segmentation 1

Dice Similarity Coefficient
D=2|AR||A|+|R|
The portion of overlap between the reference ROI and segmentation relative to the size of the reference ROI plus the size of the segmentation 1

False Negative Dice
FND=2|A¯R||A|+|R|
The volume that the segmentation missed of the reference ROI relative to the size of the reference ROI plus the size of the segmentation 0

False Positive Dice
FPD=2|AR¯||A|+R
The volume of the segmentation not found within the reference ROI relative to the size of the reference ROI plus the size of the segmentation 0

95% maximum Hausdorff Distance (HD)
H(A,R)=max(h(A,R)),h(R,A)h(A,R)=maxaA(d(A,R))&d(A,R)=mingGa-r
The maximum distance between a point in the segmentation and that of the reference ROI; for 95% maximum Hasudorrf, ±5%-ile outliers are discarded