Table 1. Conditional Probabilities for Intrinsically Disordered Segments and Protein Half-Life.

N-Terminal Disordered Segment	Half-Life				Total
		210	158	111	479
		930	1023	841	2794
Total		1140	1181	952	3273
Internal Disordered Segment
		564	432	264	1260
		576	749	688	2013
Total		1140	1181	952	3273

	Event (E)	Condition (C)	Probability (Event | Condition) = P(E⋂C)/P(C)
A	Short half-life	Long N-terminal disorder	$P(H_s|N_L)=\frac{210}{479}=0.44$
	Long N-terminal disorder	Short half-life	$P(N_L|H_S)=\frac{210}{1140}=0.18$
B	Short half-life	Internal disordered segment	$P(H_S|I_p)=\frac{564}{1260}=0.45$
	Internal disordered segment	Short half-life	$P(I_p|H_S)=\frac{564}{1140}=0.49$
C	Short half-life	Long N-terminal or internal disorder	$P(H_S|N_L\cup I_p)=\frac{653}{1513}=0.43$
	Long N-terminal or internal disorder	Short half-life	$P(N_L\cup I_p|H_S)=\frac{653}{1140}=0.57$
	Short half-life	Long N-terminal and internal disorder	$P(H_S|N_L\cap I_p)=\frac{121}{226}=0.54$
	Long N-terminal and internal disorder	Short half-life	$P(N_L\cap I_p|H_S)=\frac{121}{1140}=0.11$
	Short N-terminal and no internal disorder	Short half-life	$P(N_S\cap I_a|H_S)=\frac{487}{1140}=0.43$
	Long N-terminal and internal disorder	Long half-life	$P(N_L\cap I_p|H_L)=\frac{39}{952}=0.04$

See the top panel of this table and Figures 1 and 2 for a description of the definitions. See also Tables S3A (for part A) and S3B (for part B).