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. Author manuscript; available in PMC: 2008 Sep 23.
Published in final edited form as: Cell Mol Life Sci. 2008 Aug;65(15):2407–2418. doi: 10.1007/s00018-008-8195-y

Figure 2.

Figure 2

Long-term administration of salicylate up-regulates prestin expression. The amount of prestin mRNA was quantitatively measured by real-time RT-PCR. (A) Electrophoresis of PCR amplification of prestin from the guinea pig (GP) and mouse cochlea. The products show a single band of the same size. (B) Increase in prestin mRNA after administration of salicylate for 2 weeks. The amounts of prestin mRNA were normalized to the average amount measured from normal animals. (C) Salicylate reversibly up-regulates prestin expression. The amounts of prestin mRNA recovered were measured at 4 weeks after stopping salicylate administration.