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Evolutionary conservation of BBS5 surrounding novel missense mutation sites showing local alignment of amino acid sequence. A, c.214G>A (p.Gly72Ser) B, c.574A>G (p.Thr183Ala). Hs, Homo sapiens; M, Mus musculus; Gg, Gallus gallus; Md, Monodelfis domesticus ; Rn, Rattus norvegicus; Bt, Bos Taurus; Cf, Canis familiaris; Pt, Pan troglodytes.
