Table 2.

Adjusted Odds Ratios (95% CI) for Hs-CRP ≥ 3mg/l at Follow-up (2007–10) by Baseline (1967–73) Risk Factor Status and Single Baseline Risk Factors - The Chicago Healthy Aging Study

	N	OR (95% CI)
		Model 1*	Model 2*
Baseline RF status†
LR	259	1.00	1.00
0RF	423	1.25 (0.83–1.87)	1.35 (0.89–2.03)
1 Only RF	449	1.56 (1.05–2.31)	1.61 (1.08–2.40)
≥2 RFs	193	1.55 (0.96–2.50)	1.69 (1.04–2.75)
β coefficient/P trend‡		0.16 (0.023)	0.18 (0.014)
Single Baseline Risk Factors
Smoking Status
Never Smoker (ref.)	608	1.00	1.00
Former Smoker	397	1.14 (0.82–1.59)	1.14 (0.82–1.59)
Current Smoker	319	1.75 (1.26–2.43)	1.69 (1.21–2.36)
SBP/DBP, mmHg
≤120/≤80, no med.(ref.)	612	1.00	1.00
121–139, no med.	339	1.17 (0.84–1.63)	1.21 (0.87–1.70)
≥ 140/90 or on med.	373	0.73 (0.51–1.05)	0.75 (0.52–1.08)
Serum Total Chol., mg/dL
<200, no med. (ref.)	892	1.00	1.00
200–239, no med.	339	0.81 (0.59–1.13)	0.90 (0.64–1.27)
≥ 240 or on med.	93	1.27 (0.76–2.12)	1.46 (0.85–2.49)
BMI (kg/m2)
< 25 (ref.)	685	1.00	1.00
25–29	556	1.29 (0.95–1.75)	1.33 (0.97–1.82)
≥ 30.0	83	2.03 (1.18–3.49)	2.00 (1.16–3.46)
Diabetes	9	0.34 (0.04–2.86)	0.35 (0.04–2.93)

Abbreviations: see Table 1 footnotes.

^*Model 1: Adjusted for baseline age, sex, and race; Model 2: Adjusted for variables in Model 1 plus education attainment, and current cancer, taking aspirin, taking lipid-lowering medication, and presence of ECG major abnormalities/CVD.

^†Definition of baseline RF status: see Table 1 footnotes.

^‡P value for trend across 4 baseline RF groups.