| FaDu Cal-27 |
Network |
Beta-catenin, Tcf(Lef), TCF7L2 (TCF4), Lef-1, Axin |
CREB1, G-protein alpha-s, CREM (activators), NF-AT1(NFATC2), PKA-reg (cAMP-dependent) |
TRAF6, NF-kB, IKK-gamma, RIPK1, TAK1(MAP3K7) |
| GO Processes |
canonical Wnt signaling pathway, Wnt signaling pathway, regulation of cell differentiation, regulation of developmental process epithelium development |
glucose metabolic process, hexose metabolic process, monosaccharide metabolic process, response to oxygen-containing compound, response to endogenous stimulus |
regulation of I-kappaB kinase/NF-kappaB signaling, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB signaling, positive regulation of NF-kappaB transcription factor activity |
| p-Value |
1.19E-29 |
1.370E-18 |
8.850E-28 |
| zScore |
11.62 |
9.46 |
11.51 |
| gScore |
152.87 |
35.71 |
26.51 |
| Network |
Androgen receptor, WNT, Frizzled, p21, LRP5 |
NF-kB, TLR4, I-kB, IL-1 beta, TIRAP (Mal) |
SARS2, SEZ6L2, ANTXR2, TCP1-zeta-2, ACSL5 |
| GO Processes |
positive regulation of macromolecule metabolic process, regulation of cell cycle, positive regulation of metabolic process, Wnt signaling pathway, organ development |
MyD88-dependent toll-like receptor signaling pathway, toll-like receptor signaling pathway, positive regulation of defense response, toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway |
G-protein coupled purinergic nucleotide receptor signaling pathway, purinergic nucleotide receptor signaling pathway, G-protein coupled purinergic receptor signaling pathway, purinergic receptor signaling pathway, regulation of inhibitory postsynaptic membrane potential |
| p-Value |
6.81E-09 |
1.02E-11 |
5.12E-48 |
| zScore |
9.35 |
11.75 |
32.64 |
| gScore |
221.85 |
151.75 |
32.64 |
| SQ20B |
Network |
Beta-catenin, Tcf(Lef), TCF7L2 (TCF4), Lef-1, Axin |
CREB1, G-protein alpha-s, CREM (activators), NF-AT1(NFATC2), PKA-reg (cAMP-dependent) |
TRAF6, NF-kB, IKK-gamma, RIPK1, TAK1(MAP3K7) |
| GO Processes |
canonical Wnt signaling pathway, Wnt signaling pathway, regulation of cell differentiation, regulation of developmental process, epithelium development |
glucose metabolic process, hexose metabolic process, monosaccharide metabolic process, response to oxygen-containing compound, response to endogenous stimulus |
regulation of I-kappaB kinase/NF-kappaB signaling, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway, positive regulation of I-kappaB kinase/NF-kappaB signaling, positive regulation of NF-kappaB transcription factor activity |
| p-Value |
1.190E-29 |
1.370E-18 |
8.850E-28 |
| zScore |
11.62 |
9.46 |
11.51 |
| gScore |
152.87 |
35.71 |
26.51 |
| SCC-25 |
Network |
ESR1 (nuclear), TPL2(MAP3K8), IL-6, PKC-delta, HMGB1 |
GLCCI1, MBLAC2, NSL1, KPR2, Cathepsin F |
IFT52, FLJ32115, SDOS, DGCR2, C1orf74 |
| GO Processes |
toll-like receptor TLR6:TLR2 signaling pathway, toll-like receptor TLR1:TLR2 signaling pathway, toll-like receptor 2 signaling pathway, positive regulation of defense response, positive regulation of response to stimulus |
succinate metabolic process, glycine decarboxylation via glycine cleavage system, single-organism metabolic process, succinyl-CoA metabolic process, glycine catabolic process |
cellular glucuronidation, uronic acid metabolic process, glucuronate metabolic process, flavonoid glucuronidation, flavonoid biosynthetic process |
| p-Value |
8.33E-05 |
6.83E-37 |
8.97E-36 |
| zScore |
5.87 |
29.51 |
28.54 |
| gScore |
649.62 |
29.51 |
28.54 |
