Table 2. Differentially expressed genes in erlotinib-resistant HNSCC cells compared to erlotinib-sensitive HNSCC cells.
| Gene symbol | Gene description | Fold Change (ER vs ES)* | |||
|---|---|---|---|---|---|
|
| |||||
| FaDu | SQ20B | Cal-27 | SCC-25 | ||
| LCN2 | Neutrophil gelatinase associated lipocalin | 34.1954 | 4.7502 | 5.27695 | 2.24133 |
| CFB | Complement factor B | 20.7817 | 6.6424 | 7.00509 | 2.07181 |
| CYP1B1 | Cytochrome P4501B1 | 19.0664 | 6.14312 | 3.05695 | 4.98498 |
| MUC1 | Mucin 1 | 6.81529 | 2.09463 | 2.1252 | 3.9803 |
| SASH1 | SAM and SH3 domain containing protein 1 | 6.44004 | 4.81275 | 3.18798 | 2.6359 |
| IL6 | Interleukin 6 | 4.92215 | 6.08678 | 4.82705 | 2.26208 |
| TIMP2 | Tissue inhibitor of metalloproteinase 2 | 3.95348 | 2.95491 | 2.06882 | 2.35323 |
| H19 | Long non-coding RNA | 3.76061 | -3.39578 | -3.1987 | 2.96592 |
| ULBP1 | NKG2Dligand 1 | 2.48632 | 6.95989 | 3.08112 | -2.09594 |
| SLC1A4 | Neutral amino acid transporter A | 2.46418 | 4.21706 | 3.87978 | -2.30851 |
| PCK2 | Phosphoenolpyruvate carboxykinase 2 | 2.21638 | 3.07228 | 4.80155 | -2.2808 |
| FGFBP1 | Fibroblast growth factor binding protein 1 | -2.93184 | -11.636 | -2.32586 | -2.75626 |
| SFN | Stratifin | -3.51717 | -2.51662 | -3.28222 | -2.08091 |
*
ES: erlotinib-sensitive
ER: erlotinib-resistant