Table 2.

Descriptions of time points and endpoints assessed during five-day embryonic zebrafish bioassay

Abbreviation	Endpoint Description	Assessed Time Point (hours post fertilization)
MO24	Mortality	24
DP24	Delayed developmental progression	24
SM24	Reduced or excessive frequency of zebrafish spontaneous tail coiling	24
NC24	Notochord malformations	24
MORT	Total mortality	120
YSE_	Yolk sac edema	120
AXIS	Abnormal body axis curvature such as lordosis or scoliosis of the spine	120
EYE_	Eye malformations such as large or small eyes	120
SNOU	Snout malformations	120
JAW_	Jaw malformations	120
OTIC	Otic vesicle malformations	120
PE__	Pericardial edema	120
BRAI	Brain malformations such as edema	120
SOMI	Abnormal somite development	120
PFIN	Pectoral fin malformations	120
PIG_	Abnormal pigmentation (hypo or hyper pigmentation)	120
CIRC	Abnormal circulation or vasculature	120
TRUN	Truncated body	120
SWIM	Abnormal swim bladder development	120
NC__	Notochord malformations	120
AFTD	Total mortality combined with any malformation at 120	120