Table 3.

Pathological abnormalities of ALS2^−/− mice

Group	CSMN	CST	SMN	VR	Purkinje cells
Cai [11]	NS	NA	NS	NA	NS
Hadano [12]	NS	NA	NS	Reduced1	Reduced2
Devon [13]	Soma size reduced	NA	NS	NS	NS
Yamanaka [14]	NS	Swollen, degenerating	NS	NS	NS
Julien [15]	NA	Degeneration	NA	NA	NA
Deng [16]	NS	Degeneration	NS	NA	NA

CSMN = Corticospinal motor neurons; CST = corticospinal track; SMN = spinal motor neuron; VR = ventral root.

¹Small caliber axons.

²Calbindin-positive.