TABLE II.

Summary of local maxima for the ANCOVA VBM results

	Labels	Cluster local maxima of peak voxel(s)	Brodmann areas involved
Young greater than older adults	Bilateral Sylvian fissure: Insula, superior  and transverse temporal gyri	46, 2, −7/−44, −2, −2	13, 22, 41, 42
	Thalamus/putamen	1, −3, 11/−20, 6, 1	N/A
	Bilateral pre- and postcentral gyri	50, −33, 58/−47, −14, 46	2, 3, 4
	Bilateral frontal areas: Superior, middle,  and inferior frontal gyri	31, 29, 52/−33, 57, 19	6, 8, 9, 10, 45
	Bilateral interparietal lobule	44, −49, 55/−41, −57, 50	40
	Occipital areas: Left superior occipital  and fusiform gyri, right precuneus	18, −54, 31/−34, −93, 23,  and −56, −56, −29	19, 37
Young greater than middle-aged adults	Right middle frontal gyrus	3, 48, 29	9
Middle-aged greater than  older adults	Bilateral Sylvian fissure: Insula, superior  and transverse temporal gyri	39, −18, 19/−40, −11, −16	13, 22, 41
	Thalamus	−1, −16, −8	N/A
	Bilateral caudate\putamen	6, 15, 1/−7, 10, 6\22, 4,  −5/−21, 3, −6	N/A
	Bilateral precentral gyri	44, −13, 45/−47, −15, 45	4, 6
	Bilateral frontal areas: Superior, middle,  and inferior frontal gyri	37, 23, 5/−17, 43, 44	6, 8, 9, 10, 45
	Left interparietal lobule	−40, 40, 28	~40
	Left inferior occipital gyrus	−42, −82, −9	~19

FWE corrected for multiple comparisons; ICV entered as the covariate.