Score (dbtype)
|
Categorical Prediction
|
SIFT (sift) |
D: Deleterious (sift<=0.05); T: tolerated (sift>0.05) |
PolyPhen 2 HDIV (pp2_hdiv) |
D: Probably damaging (>=0.957), P:possibly damaging (0.453<=pp2_hdiv<=0.956); B:benign (pp2_hdiv<=0.452) |
PolyPhen 2 HVar (pp2_hvar) |
D: Probably damaging (>=0.909), P:possibly damaging (0.447<=pp2_hdiv<=0.909); B:benign (pp2_hdiv<=0.446) |
LRT (lrt) |
D: Deleterious; N: Neutral; U: Unknown |
MutationTaster (mt) |
A” (“disease-causing-automatic”); “D” (“disease-causing”); “N” (“polymorphism”); “P” (“polymorphism-automatic”) |
MutationAssessor (ma) |
H: high; M: medium; L: low; N: neutral. H/M means functional and L/N means non-functional |
FATHMM (fathmm) |
D: Deleterious; T: Tolerated |
MetaSVM (metasvm) |
D: Deleterious; T: Tolerated |
MetaLR (metalr) |
D: Deleterious; T: Tolerated |
CADD |
Combined Annotation Dependent Depletion |