Table 3.
Mouse | Rat | Total | ||
---|---|---|---|---|
Antibody | Shorter Labeling1 | Longer Labeling2 | Shorter Labeling | |
Cx36 | 408 (92%) | 137 (88%) | 62 (85%) | 607 (90%) |
Cx36 + Cx45 | 29 (7%) | 19 (12%) | 10 (14%) | 58 (9%) |
Cx45 | 5 (1%) | 0 (0%) | 1 (1%) | 6 (1%) |
Total | 442 (100%) | 156 (100% | 73 (100%) | 671 (100%) |
Shorter labeling was defined as 1– 4.4 h for primary and 12–17 h for secondary antibody labeling; no significant differences were noted between 1–1.2 h and 4.4 h for primary antibodies.
Longer labeling was defined as 5.3– 6.8 h for primary and 21.5 h for secondary antibodies.
Numbers in parentheses indicate percentage of labeled gap junctions found in each labeling protocol. These data do not include the 160-plus Cx36 and Cx36+Cx45-containing gap junctions found in the double replicas (see Table 4).
These data do not include the 160-plus Cx36 and Cx36+Cx45-containing gap junctions found in the double-replicas (See Table 4).