Table 2.
Correlation between long non-coding RNA subclasses and genomic aberrations (one-sided Fisher's exact test).
| Aberration | Cluster 1 (n = 138) | Cluster 2 (n = 110) | Cluster 3 (n = 186) | Cluster 4 (n = 34) | P value |
|---|---|---|---|---|---|
| chr3p25.3_Loss | 121 (87.7%) | 60 (54.5%) | 163 (87.6%) | 3 (8.8%) | 3.98E-26 |
| chr3p21.32_Loss | 122 (88.4%) | 61 (55.4%) | 161 (86.6%) | 5 (14.7%) | 8.78E-23 |
| chr1q43_Loss | 5 (3.6%) | 0 | 5 (2.7%) | 12 (35.3%) | 4.60E-10 |
| chr3p12.3_Loss | 83 (60.1%) | 46 (41.8%) | 117 (62.9%) | 3 (8.8%) | 8.16E-10 |
| chr1p31.1_Loss | 7 (5.1%) | 11 (10.0%) | 12 (6.4%) | 16 (47.1%) | 1.33E-08 |
| chr3p12.2_Loss | 74 (53.6%) | 43 (39.1%) | 107 (57.5) | 3 (8.8%) | 8.51E-08 |
| chr5q35.1_Gain | 83 (60.1%) | 47 (42.7%) | 111 (59.7%) | 5 (14.7%) | 5.14E-07 |
| chr8q24.22_Gain | 4 (2.9%) | 24 (21.8%) | 11 (5.9%) | 2 (5.9%) | 3.89E-06 |
| chr1p36.23_Loss | 10 (7.2%) | 12 (10.9%) | 17 (9.1%) | 15 (44.1%) | 3.90E-06 |
| chr9p21.3_Loss | 13 (9.4%) | 37 (33.6%) | 26 (14%) | 3 (8.8%) | 4.84E-06 |
| chr13q13.3_Loss | 5 (3.6%) | 14 (12.7%) | 4 (2.1%) | 7 (20.6%) | 2.00E-05 |
| chr3q11.2_Loss | 41 (29.7%) | 19 (17.3%) | 54 (29%) | 0 | 3.93E-05 |
| chr17q24.3_Gain | 4 (2.9%) | 6 (5.4%) | 4 (2.1%) | 7 (20.6%) | 0.000579 |
| chr14q31.1_Loss | 30 (21.7%) | 38 (34.5%) | 67 (36%) | 3 (8.8%) | 0.000656 |
| chr9p23_Loss | 12 (8.7%) | 28 (25.4%) | 24 (12.9%) | 5 (14.7%) | 0.003035 |
| chr2q37.3_Loss | 7 (5.1%) | 9 (8.2%) | 12 (6.4%) | 9 (26.5%) | 0.00306 |
| chr3q26.32_Gain | 4 (2.9%) | 17 (15.4%) | 15 (8.1%) | 4 (11.8%) | 0.003111 |