Table 2.
Other Outcome Measures
| OUTCOME MEASURE |
REFERENCE FOR STUDIES USED |
INTER-RATER RELIABILITY |
TEST-RETEST RELIABILITY |
SENSITIVITY TO CHANGE |
CLINICALLY MEANINGFUL CHANGE |
ENDORSEMENT |
|---|---|---|---|---|---|---|
| Mood/Behavioral | ||||||
| NPI | 6, 22–27, 31–34 & 37 | High | Moderate to high | Yes | 8 points | Recommended |
| CSDD | 31 | High | High | Yes | Not established for dementia | Recommended |
| BPRS | 38 | Moderate | Not established for dementia | Not established for dementia | Not established for dementia | Suggested |
| Activities of Daily Living and Quality of Life | ||||||
| ADCS-ADL | 6, 25, 27, 36 & 37 | High | High | Yes | 2 points | Recommended |
| QOL-AD | 7 | High | High | Yes | Not established for dementia | Recommended |
| DAD | 22, 26, 33 & 34 | High | High | Yes | Not established for dementia | Recommended |
| SE-ADL | 26 | Moderate | Not established for dementia | Not established for dementia | Not established for dementia | Suggested |
| PDQ-39 | Not used | Not established for dementia | Moderate | Not established for dementia | Depends on subsection, but has been established | Suggested |
| UPDRS-ADL | 31 & 38 | Not established for dementia | Not established for dementia | Not established for dementia | Not established for dementia | Listed |
| Global | ||||||
| CGI | 22, 29, 35 & 38 | Moderate | Moderate | Yes | Not established for dementia | Recommended |
| ADCS-CGIC | 6, 25 & 27 | Not established for dementia | High | Yes | 1–2 points | Suggested |
| CIBIC+ | 24, 26 & 32 | Low | Moderate | Yes | Not established for dementia | Suggested |
| Caregiver Burden | ||||||
| ZBI | 6 & 30 | Not established for dementia | High | Yes | 13 points | Suggested |
- “Recommended”: the outcome measure has been applied to PDD patients and has been found valid, reliable and responsive in psychometric studies in studies of PDD or other dementias
- “Suggested”: the outcome measure has been applied to PDD patients and psychometric studies are promising (“moderate” to “high” parameters), but not yet complete in dementia populations and/or some psychometric properties are suboptimal (“low”)
- “Listed”: the outcome measure has been applied to PDD patients but psychometric studies have demonstrated disappointing data (“low” parameters) and/or have not yet been performed in dementia populations
Abbreviations: NPI: Neuropsychiatric Inventory; BPRS: Brief Psychiatric Rating Scale: CSDD: Cornell Scale for Depression in Dementia; ADCS-ADL: Alzheimer’s Disease Cooperative Study-Activities of Daily Living Scale; QOL-AD: Quality of Life in Alzheimer’s Disease Scale; DAD: Disability Assessment for Dementia; SE-ADL: Schwab and England ADL scale; PDQ-39: Parkinson’s Disease Questionnaire-39; UPDRS-ADL: Unified Parkinson Disease Rating Scale-Activities of Daily Living; CGI: Clinical Global Impression scale; ADCS-CGIC: Alzheimer’s Disease Cooperative Study – Clinician’s Global Impression of Change; CIBIC+: Clinician Interview Based Impression of Change with caregiver input; ZBI: Zarit Burden Interview-Caregiver Burden Assessment