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. Author manuscript; available in PMC: 2015 Jul 21.
Published in final edited form as: Mol Cell. 2015 May 14;58(6):1040–1052. doi: 10.1016/j.molcel.2015.04.018

Figure 5. Validation of the AM-Bound ECD Heterodimer Structure for the Intact AM1 Receptor Transiently Expressed in COS-7 Cells.

Figure 5

Concentration-response curves for each of the CLR (A) or RAMP2 (B) alanine substitution mutants tested with hAM in cAMP signaling assays. Data are represented as mean ± SEM. See also Table S4.