Table 1b.

Basal activity (LOF).

Receptor	BW	Mutation	Ref.
MC4R	1.57	I→T	48,153
MC4R	2.62	I→S,T	19,25,173,184,185 16,19,25,48,186
MC4R	3.24	I→T	45
MC4R	3.53	T→I	48
MC4R	4.41	R→W	25,45,48,172,173,184
MC4R	4.50	W→C	95
MC4R	6.34	A→E	45,184
MC4R	6.42	G→S	45,48,185
MC4R	6.61	C→R	25,173,187
MC4R	7.52	I→T	48,172