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ICa,L characteristics
| Control | Ivabradine 3 μM (n=12) | Ivabradine 10 μM (n=9) | Ivabradine 30 μM (n=9) | |
|---|---|---|---|---|
| Peak ICa,L density (pA/pF) | 13.9±1 | 13.2±1 (P=0.953) | 9.85±1.4* (P=0.0003) | 8.1±1*,# (P<0.001) |
| Voltage at peak ICa,L (mV) | −5.55±1 | −5.4±0.7 (P=0.84) | −5±0.1 (P=1) | −6±0.8 (P=0.98) |
p<0.05 vs. control,
p<0.05 vs. IVA 3μM.
