Skip to main content
. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Cell Mol Gastroenterol Hepatol. 2015 Sep 1;1(5):503–515. doi: 10.1016/j.jcmgh.2015.06.008

Figure 8. As-miR-221-5p regulates inflammation in DSS-induced colitis models.

Figure 8

(A) Timeline of as-miR-221-5p treatment in 1% DSS-induced colitis. (B) Histological changes in colons of with controls or as-miR-221-5p treated C57BL6/J mice in DSS colitis model. Scale bar, 100μm. (C). Expression level of miR-221-5p after intracolonic administration of as-MiR-221-5p. * indicates p<0.05 compared with controls (n=6). (D). Histopathology sore of as-miR-221-5p treated mice with DSS-induced colitis. (E). The PMN infiltration sore of as-miR-221-5p treated mice with DSS-induced colitis. (F). Expression of TNF-α, Cxcl10 and Col2α1 in the colon tissue of as-miR-221-5p or anti-miR-control treated DSS-induced colitis models. * indicates p<0.05 compared with controls (n=6).