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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Mol Oncol. 2015 Aug 6;10(1):1–23. doi: 10.1016/j.molonc.2015.07.005

Figure 10. Inhibition of clathrin-mediated uptake of rLOX-PP-Atto565 in presence or absence of dynasore.

Figure 10

(A) After 3 hours, rLOX-PP-Atto565 uptake quantified with flow cytometry in absence (gray bar) and presence of 100 μM dynasore (white bar); *, significant inhibition of uptake in PC3 cells only (p < 0.000125; n=3). Up-regulation occurred in all other cell lines. (B) The LIVE/DEAD® Fixable Near-IR stain assay was employed to determine the percentage of live cells. NT (dark gray bars), non-treated control cells; rLOX-PP-Atto565 (light gray bars); rLOX-PP-Atto565 plus dynasore (white bars). Data are means +/− SD, n = 3.