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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Pediatrics. 2015 Nov;136(5):e1169–e1177. doi: 10.1542/peds.2015-1364

Table 4.

Relative Risk Ratio for Misuse of Prescription Opioids in Follow-ups 1–3 for Respondents with vs. without Legitimate Prescription Opioid Use by 12th Grade, by Risk Strata (95% Confidence Intervals in Parentheses)

Strata # (1) (2) (3) (4) (5) (6) (7) (8)
Predicted
Probability of
Opioid
Misuse After
High School
0 to
<1.75%
1.75 to
<3%
3 to
<5%
5 to<10% 10 to
<20%
20 to
<30%
30 to
<45%
>=45%

Legitimate
prescription
opioid use
by 12th
grade
.97
(.22–4.29)
3.01**
(1.79 –5.07)
1.95*
(1.15–3.34)
1.24
(.81–1.91)
.98
(.66–1.44)
1.06
(.64–1.73)
.56
(.31–1.01)
.86
(.49–1.63)
*

p<.05;

**

p<.01

Note: The risk ratios in stratums 2 and 3 are significantly higher than those in the other stratums combined, as tested with multiplicative interaction terms. Test models included (a) all the predictors in Model 2 of Table 2, (b) an indicator variable for risk stratum and (c) a multiplicative interaction term of the risk stratum indicator and legitimate opioid prescription by 12th grade. In separate models interactions were statistically significant (p<.05) when including an indicator for risk stratum 2, risk stratum 3, and an indicator for risk strata 2 and 3 combined.