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. Author manuscript; available in PMC: 2015 Nov 25.

Published in final edited form as: Nat Commun. 2015 Oct 13;6:8533. doi: 10.1038/ncomms9533

Co-staining with CD3 and B220 revealed that lung granulomas following infection with MtbΔsigH (a) exhibited a significantly increased iBALT response relative to infection with Mtb (b). The white bar represents 500 µm. Data from multiple lesions from six different animals were used in the analyses. (c) The percentage of area occupied by iBALT follicles relative to total lung area was analyzed in animals challenged with Mtb () and MtbΔsigH (). *P<0.05 (student’s t-test). Data are means ± S.D. Samples from 4–5 animals in each group were used for analysis.

Inline graphic — Co-staining with CD3 and B220 revealed that lung granulomas following infection with MtbΔsigH (a) exhibited a significantly increased iBALT response relative to infection with Mtb (b). The white bar represents 500 µm. Data from multiple lesions from six different animals were used in the analyses. (c) The percentage of area occupied by iBALT follicles relative to total lung area was analyzed in animals challenged with Mtb () and MtbΔsigH (). *P<0.05 (student’s t-test). Data are means ± S.D. Samples from 4–5 animals in each group were used for analysis.