1) Outcome: IR | Predictors: stage, age, gender, cohort group (high- versus low-responder arms) |
2a) Outcomes: OS, DFS | Predictors: stage, age, gender, immune response (all participants) |
2b) Outcomes: OS, DFS | Predictors: stage, age, gender, immune response (only participants from high responder arms (Mel43 A & C) and (Mel44 A & B) |